Abstract
The access to antiretroviral treatment has contributed to a global decrease in the number of new HIV infections, although the HIV pandemia continues to be a global challenge. In Spain, HIV transmission is mainly attributed to sexual relations among men. A 46 % of the new diagnoses has made lately. HIV infects CD4+ T lymphocytes, inducing an important reduction of the number of these cells, favoring the opportunistic and neoplastic entities defining AIDS. Likewise, HIV infection induces a persistent immune activation and a chronic inflammatory state, both implicated in the decrease of CD4+ T cells number, premature aging, multiorganic damage and non-AIDS defining neoplasias. The antiretroviral therapy has a limited activity against these immune and inflammatory activation-related diseases.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
