Infantile manifestation of vanishing White Matter disease

Abstract

Among childhood leukodystrophies, Vanishing White Matter Disease (VWMD) has recently been recognized as one of the most frequent types. The age at manifestation is usually between two and six years, rarely at a younger age. Minor head trauma and fever are thought to be triggering factors. We report a boy in whom a very severe course of VWMD started at the end of the first year of life.