Abstract

Infantile cortical hyperostosis (ICH), also known as Caffey disease, Caffey-Silverman syndrome, or Smyth syndrome, is a genetic disorder represented by an infantile episode of massive, subperiosteal, new bone formation that typically involves diaphysis of the long bones, mandible, and clavicles.1 The disease begins in early infancy and usually is self-limiting. It is characterized by unusual irritability, soft tissue swelling, and cortical hyperostosis.2,3 A clinical triad includes fever, soft tissue swelling, and hyperirritability.

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