Abstract

Infant botulism is an uncommon disease with a challenging diagnosis which is often confused with other diseases. This is a report of a case of infant botulism with no history of honey ingestion and responds well to equine immunoglobulin due to the low prevalence and importance of the mentioned disease.

Highlights

  • Botulism is an acute paralytic disease which presents with a descending and symmetrical flaccid paralysis while the patient has no fever[1]. The cause of this flaccid paralysis is the inhibition of the releasing acetylcholine neurotransmitter in voluntary muscles and autonomic neuromuscular junction by toxin botulism caused by Clostridium botulinum.[1,2]

  • It should be noted that infant botulism is one of the types of botulism which is mainly observed in infants under 6 months it can occur in the age range of one day to one year

  • The present report introduces an infant with botulism diagnosis who was treated with equine botulinum antitoxin at our medical center due to the lack of BabyBIG

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Summary

Background

Botulism is an acute paralytic disease which presents with a descending and symmetrical flaccid paralysis while the patient has no fever[1]. It was decided to send the patient to an equipped center because the patient had no sign of recovery and was transferred to the pediatric intensive care unit of our center He was hospitalized due to severe weakness and poor feeding in the previous center. The infant was conscious while he had an expressionless face and bilateral ptosis His crying was weak, and the inability of controlling the neck was noted when he was in his mother’s arms. He had no gag reflex by examining the pharynx and, in general, he suffered from hypotonia. He was relieved in a good general condition after about three and a half weeks of hospitalization

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