Abstract
The human population remains in the threat of the Pandemic of COVID 19 till date with one another faces of it. The second wave of the pandemic led population into vain again with yet another danger of the third wave. The use of the steroids for controlling and treatment of the upsurge during the second wave remained a trend. The uncontrolled use of steroids invites the secondary infection mucormycosis also called black fungus which affected the population badly. Mucormycosis is opportunistic infection that acquired immune compromised patients with COVID 19 and steroids in treatment paradigm. Most of the patients with high blood glucose levels and diabetes faced this threat and created pandemic in pandemic again. The reviews focus on the positive and negative both prospects of the steroidal use and how steroids were the leading cause of the blowout of the Black fungus infection.
Highlights
The world was shaken by the emerging threat with the name of novel corona virus (COVID 19) in the year 2019
The biggest challenges for the survival of the human population came into existence in the form of the SARS COVID 19 which is still being a cause of concern
The studies are the sole source of the incorporation of the steroids in the treatment regimen and various drug candidates suited for the situation to be controlled
Summary
The world was shaken by the emerging threat with the name of novel corona virus (COVID 19) in the year 2019. Hypoxia, compromised immune system, diabetic ketoacidosis or metabolic alkalosis proved to be the favourable environment for the development and further spread of the fungal infections. The aim of the review is to enlighten the effect of the ethical and unethical perspective of steroids use in the COVID19 and how the steroids were part of the mucormycosis yet another threat which proved to be havoc for the human survival. Type II transmembrane serine protease enzyme found in the host cells processes the complex of the S protein ACE II proteolytically. This dispensation cleaves the ACE II and leads to the entry of virus into the cells of host [11]. The schematic representation shows how the virus is entered into the host body and completes its cycle of replication and proven to be really destructive for the human body
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