Abstract

This study was designed to investigate conditions of the extraction general properties of hemp (Cannabis sativa L.) root using response surface methodology (RSM) for extract. Extraction time, temperature, and hemp root/water ratio parameters were selected to the optimum infusion point for hemp root extract in terms of the best physical properties and antioxidant activities with seven responses to use prediction power with 20 trial patterns. Some of the lowest and highest values of the responses were found as 4.51–71.54 mg gallic acid/ kg for TPC, and 1.52–10.13 millimolar (mM) Troloks for DPPH. The optimal point for hemp root extraction was found: hemp root/water ratio% of 10,the temperature of 95 °C, time of 19.39 min with%91 desirabilities. This study indicated that optimizing hemp root infusion could be useful for related brewing industries and pharmaceutical industries for different purposes. The model has the potential to reduce both processing costs and time while enhancing its ability to support extract color and functionality in various hemp root-derived beverage products.

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