Abstract

Localized heat induction using magnetic nanoparticles under an alternating magnetic field is an emerging technology applied in areas including, cancer treatment, thermally activated drug release and remote activation of cell functions. To enhance the induction heating efficiency of magnetic nanoparticles, the intrinsic and extrinsic magnetic parameters influencing the heating efficiency of magnetic nanoparticles should be effectively engineered. This review covers the recent progress in the optimization of magnetic properties of spinel ferrite nanoparticles for efficient heat induction. The key materials factors for efficient magnetic heating including size, shape, composition, inter/intra particle interactions are systematically discussed, from the growth mechanism, process control to chemical and magnetic properties manipulation.

Highlights

  • Ferrite (MFe2 O4, M = moment 5μB (Mn), Fe, Co, Ni and Zn) magnetic nanoparticles have attracted profuse attention because they are at the interfaces of chemistry, physics and biology, due to their remarkable size and shape-dependent magnetic properties [1,2,3]

  • In the nano-regime the magnetic properties such as coercivity (HC ), saturation magnetization (MS ) and susceptibility (χ) strongly vary with the size, shape, and composition of the magnetic nanoparticles [2,6,10]. These unique magnetic properties, small size and biocompatibility make them promising in various biomedical applications, for instance contrast enhancement in magnetic resonance imaging (MRI), nano-sized carrier in drug delivery, mediators in converting electromagnetic energy to heat, and as magnetic-targeting and bio-sensing agents [11,12,13,14,15]

  • We focus onof the chemical synthesis, particularsize, the organic phase synthesis, of a series of magnetic nanoparticles (MNPs) phase synthesis, a series of MNPs withincontrolled composition, and morphology

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Summary

Introduction

In the nano-regime the magnetic properties such as coercivity (HC ), saturation magnetization (MS ) and susceptibility (χ) strongly vary with the size, shape, and composition of the magnetic nanoparticles [2,6,10] These unique magnetic properties, small size and biocompatibility make them promising in various biomedical applications, for instance contrast enhancement in magnetic resonance imaging (MRI), nano-sized carrier in drug delivery, mediators in converting electromagnetic energy to heat, and as magnetic-targeting and bio-sensing agents [11,12,13,14,15].

Characteristics of Magnetic Nanoparticles and Inductive Heating Principles
Effects of Magnetic Anisotropy and Magnetic Susceptibility
Size Effects
O4different
Composition Effects
Shape Effects
Osphere-shaped
O4 the
Effects of Intraparticle Interactions
Findings
Conclusion

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