Induction of specific-locus and dominant lethal mutations in male mice by trophosphamide

U.H Ehling,A Neuhäuser-Klaus

doi:10.1016/0027-5107(94)90296-8

Induction of specific-locus and dominant lethal mutations in male mice by trophosphamide

U.H Ehling, A Neuhäuser-Klaus

https://doi.org/10.1016/0027-5107(94)90296-8

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Journal: Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis	Publication Date: May 1, 1994
Citations: 18

Affiliation: Institute of Bioinformatics and Systems Biology

#Dominant Lethal Mutations #Lethal Mutations In Male Mice + Show 8 more

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Abstract

Trophosphamide induced dominant lethal and specific-locus mutations in spermatozoa and spermatids of mice. The induction pattern of specific-locus and dominant lethal mutations shows two maxima in the mating intervals 1–4 and 9–16 days post treatment. The nature of induced mutations is suggested to be intergenic.

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