Abstract

Objective: Increased presence of monocytes/macrophages has been reported in the peritoneal fluid (PF) of women with endometriosis. Monocyte chemotactic protein-1 (MCP-1) plays a major role in the recruitment of monocytes into the peritoneal cavity. We have previously reported that oxidative stress and mildly oxidized form of low density lipoprotein (mo-LDL) might be involved in generating the inflammatory milieu in the PF. This study was designed to elucidate the effect of mo-LDL and PF of women with endometriosis on MCP-1 production by peritoneal mesothelial cells, endometrial stromal cells and endometrial epithelial cell line (EM42 cells).

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