Abstract
Abstract. The intra‐uterine volume of 10 obstetrically normal nulliparous midtrimester patients was increased by the intra‐amniotic instillation of 350 ml Macrodex. There were 2 treatment failures due to the rupturing of the fetal membranes within 2 hours of the instillation. In all the remaining 8 patients the intra‐uterine pressure increased gradually, following volume increase. However, it only reached the magnitude demanded for clinical abortion in 4.
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