Abstract
Induction of metallothionein (MT) in liver of the subtropical fish, bluestriped grunt ( Haemulon sciurus), has been studied after cadmium injection. Hepatic MT was assayed by a heterologous radio immunoassay (RIA) for bluestriped grunt, using antiserum raised against MT from perch ( Perca fluviatilis). Two laboratory experiments were performed: a dose-response experiment and a time-course experiment. Hepatic MT was significantly induced in a dose-dependent manner in response to intraperitoneal injection of CdCl 2. Maximum MT levels were observed in the 2200 μg Cd/kg group, where MT values were three times higher than in the control group. In the time-course experiment, elevated MT levels were found 2 days after injection and the maximum was reached after 6 days. MT values in fish 6 days after treatment were increased five times compared to the control group.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.