Induction of labour in mid-trimester pregnancy using double-balloon catheter placement within 12\u2009h versus within 12\u201324\u2009h

Jing Peng,Xuan Zheng,Shuguo Du,Heng Yin,Ruobing Li,Shiyao Wu,Min Li,Yun Zhao

doi:10.1186/s12884-020-03513-7

Abstract

BackgroundThis study aims to evaluate the efficacy and safety of the induction of labour in mid-trimester pregnancy using a double-balloon catheter (DBC) within 12 h versus within 12–24 h.MethodsIn this retrospective study, a total of 58 pregnant women at 14 + 0 weeks to 27 + 6 weeks of gestation were enrolled as research subjects, and they underwent the intended termination of pregnancy at our birth centre from January 1, 2017, to June 31, 2019. Based on the duration of DBC, the patients were divided into two groups, namely, the DBC group within 12 h and the DBC group within 12–24 h.ResultsAll 58 cases were successful vaginal deliveries, and no one chose to undergo caesarean section. The success rate of induction (successful abortion of the foetus and placenta without the implementation of dilation and evacuation) was higher in the DBC group within 12–24 h (96.3%, 29/31) than in the DBC group within 12 h (71.0%, 18/27) (p < 0.05). Additionally, the time from DBC removal to delivery in the DBC group within 12–24 h was significantly shorter than that in the DBC group within 12 h (3.0 h versus 17.8 h) (p < 0.05), and the degree of cervical dilation after DBC removal in the DBC group within 12–24 h was larger than that in the DBC group within 12 h (p < 0.05).ConclusionIn the clinic, the placement time of DBC generally lasts for approximately 12 h. However, considering that the cervical condition is immature in the mid-trimester, properly extending the placement time of DBC to 24 h will benefit cervical ripening and reduce the chance of dilation and evacuation.

Highlights

This study aims to evaluate the efficacy and safety of the induction of labour in mid-trimester pregnancy using a double-balloon catheter (DBC) within 12 h versus within 12–24 h
We evaluated the efficacy of DBC within 12–24 h versus DBC within 12 h on the termination of mid-trimester pregnancy from January 1, 2017, to June 31, 2019 in our birth centre
Cervical ripening before and after DBC in the 12-h group and in the 24-h group There was no significant difference in cervical ripening between the two groups according to Bishop scores (p > 0.05)

Summary

Introduction

This study aims to evaluate the efficacy and safety of the induction of labour in mid-trimester pregnancy using a double-balloon catheter (DBC) within 12 h versus within 12–24 h. Induction of labour is a common obstetric intervention that occurs in a high proportion of pregnancies [3]. Both medical and surgical methods are available for midtrimester pregnancy. Medical methods such as mifepristone plus misoprostol are more common in the United Kingdom, Europe and developing countries [4, 5]. The common approach for the induction of labour in mid-trimester pregnancy is to use pharmacological and mechanical devices. Balloon treatment is well accepted by pregnant women [11, 12] and will not cause excessive stimulation or poor foetal heart monitoring changes [13]

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