Abstract
The induction of hepatitis in adult hamster by H-1 virus was documented by demonstrating an increase in serum SGOT and SGPT at 3-9 wk postinoculation. The electrophoresis pattern of LDH isoenzymes showed a marked increase in the liver fraction (fraction 5) indicating liver damage in infected hamsters. The pathology displayed in diseased livers revealed a focal degeneration of hepatic cells although infiltration of white cells was not observed. H-1 virus is apparently capable of producing hepatitis (without symptoms) in adult hamsters as well as cause hepatitis and severe cerebral disease in newborn hamsters.
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Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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