Abstract

THERE have been many studies of the effects of ethyl alcohol on reproductive performance and of the genetic aspects of this relationship1–10. But in spite of extensive investigations of the genetic determination of alcohol preference in experimental animals, there has been little research on other genetic aspects of alcohol consumption11–13. It has been assumed for a long time that alcohol presents no genetic hazard. Using the dominant lethal technique, we have now found that in mice ethyl alcohol can be mutagenic when given under certain conditions.

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