Abstract
Induction of chromosomal aberrations in mitotic chromosomes of fish Boleophthalmus dussumieri after exposure in vivo to antineoplastics Bleomycin, Mitomycin-C and Doxorubicin
Highlights
Boleophthalmus dussumieri a pop-eyed edible mudskipper is a widely occurring species along the muddy coasts of back waters and creeks of western India
The results revealed dose and time dependent increase in the chromosomal aberrations after treatments with all antineoplastic drugs
We report here the clastogenic potentials of three antineoplastic antibiotics viz Bleomycin, Mitomycin-C and Doxorubicin on the mitotic chromosomes of Boleophthalmus dussumieri
Summary
The results revealed dose and time dependent increase in the chromosomal aberrations after treatments with all antineoplastic drugs. Krishnaja and Rege (1982) reported increase in the frequency of chromosomal aberrations from the fish Boleophthalmus dussumieri after in vivo exposure to Mitomycin-C and heavy metals mercury, selenium and chromium.
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