Abstract
The term thermotolerance was coined by Henle and Dethlefsen in connection with a review on the hyperthermic treatment of cancer, but, in addition to its important medical implications, the phenomenon of the acquired tolerance to heat. Many aspects of heat hardening in about 60 species of the higher plants were studied by the Alexandrov’s group at the Botanical Institute in Leningrad. The particular interest in plants results from the trivial fact that, unlike animals, they are fixed in their natural habitat and thus are much less capable of minimizing their exposure to stressful conditions. The term “intrinsic heat sensitivity” is introduced to stress the fact that the cytotoxicity of a given hyperthermic treatment is dependent on the metabolic situation of the cell. Many factors influencing this cellular state may contribute positively or negatively to the survival rate after heat killing.
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