Abstract
The hypothesis is that induced pluripotent stem cells (iPSC) derived Schwann cells and/or macrophages can be transplanted into acellular nerve graft in repairing injured nervous system. The efficiency of iPSC seeded acellular nerve graft may mimic the autologous peripheral nerve graft.
Highlights
Brain and spinal cord injury conditions are non-reversible and current therapies are quite limited
The hypothesis is that induced pluripotent stem cells derived Schwann cells and/or macrophages can be transplanted into acellular nerve graft in repairing injured nervous system
The acellular grafts lost Schwann cells inside and the extracellular matrix suffers from somewhat disruption
Summary
The hypothesis is that induced pluripotent stem cells (iPSC) derived Schwann cells and/or macrophages can be transplanted into acellular nerve graft in repairing injured nervous system.
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