Abstract
IntroductionFunctional endoscopic sinus surgery (FESS) is one of the common surgical procedures requiring hypotensive anesthesia; many agents have been tried to reduce the amount of blood loss. This study aims at comparing the efficacy of two agents for providing deliberate hypotension.ObjectivesThe aim of this study was to evaluate the efficacy of esmolol and of dexmedetomidine and compare which one of the two is a better agent to produce induced hypotension during FESS.Materials and methodsThis was a comparative study conducted in a tertiary care hospital in Odisha, India. There were two study groups with 30 participants each who were given either esmolol or dexmedetomidine (group E and group DEX, respectively).ResultsEsmolol is an anti-hypertensive agent with better hemodynamic stability. The amount of drug and dose requirement was low in group DEX. The emergence time, sedation score, and time to first analgesic request were found to be highly statistically significant in group DEX.ConclusionDexmedetomidine was found to be a better agent at controlling intra-operative blood pressure than esmolol and had beneficial effects on recovery from anesthesia and analgesia.
Highlights
Functional endoscopic sinus surgery (FESS) is one of the common surgical procedures requiring hypotensive anesthesia; many agents have been tried to reduce the amount of blood loss
Another similar study conducted in Punjab reported that dexmedetomidine and esmolol provided better hemodynamic stability and more bloodless surgical field compared to nitroglycerin during FESS and that dexmedetomidine provided an additional benefit of reducing the analgesic requirements and providing postoperative sedation [10]
In a study conducted in China, the researchers tried a combination of esmolol and dexmedetomidine in nasal endoscopic surgery and both dexmedetomidine alone and dexmedetomidine combined with esmolol could effectively control hypotension, but the latter had the advantages of better blood pressure (BP) control quality, less pain, and lower probability of adverse reactions such as nausea, vomiting, and bronchospasm, which could improve the safety of nasal endoscopic surgery [11]
Summary
The aim of this study was to evaluate the efficacy of esmolol and of dexmedetomidine and compare which one of the two is a better agent to produce induced hypotension during FESS.
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