Abstract
DESPITE much work on the induction of mutations in mice by ionizing radiations1 and chemicals2–6, the possible mutagenic effects of internally administered radioisotopes have received little attention (see, however, ref. 7). Any genetic effects of radioisotopes are important from the point of view both of the hazards of radioactive fallout and of the use of certain isotopes in human medicine. We present here the results of preliminary observations of the effects of phosphorus-32 in work concerned with the evaluation of genetic hazards of certain important radio-nuclides in mice. Phosphorus-32 is known to produce mutations in Drosophila8 and in micro-organisms9.
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