Abstract
RATIONALE: Damp/moldy environments have been associated with asthma exacerbation, but mold's role in allergic asthma induction is less clear. Recently, 5 molds were statistically associated with water-damaged asthmatic homes in the Cleveland area. The asthma exacerbations were lower for asthmatic children from remediated homes compared to control asthmatics (non-remediated homes). This study's objective was to assess 2 (Scopulariopsis brevicaulis (SBE), Penicillium crustosum Group (PCG)) of these molds' potential to induce allergic responses relative to house dust mite (HDM) in our mouse allergy/asthma model.
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