Abstract

Rationale: Indole-3-acetate (IAA) is a tryptophan metabolite produced by gut microbiota and has been associated with glucose homeostasis in preclinical studies. Since bariatric surgery can promote changes in tryptophan metabolism, we evaluated the associations between IAA and biomarkers of glycemic control before and three months after of Roux-en-Y gastric by-pass surgery (RYGB).

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