Abstract
Metastatic rectal cancer requires a multidisciplinary and individualized approach.The authors describe a case report of a 48-year-old man with recurrence of rectal adenocarcinoma that underwent multimodal treatment, which included chemotherapy with biologic agents, cytoreduction surgery with hyperthermic intraperitoneal chemotherapy, and radiotherapy with improvement in progression-free survival and overall survival.
Highlights
Peritoneal carcinomatosis from colorectal cancer (CRC) represents a group of patients with metastatic disease associated with poor prognosis.In metastatic setting, chemotherapy (CTX) eventually with association of biologic agents is the standard of care, with improvement in progression-free survival and overall survival (OS)
After re-staging with computed tomography (CT) and positron emission tomography–computed tomography (PET–CT), both suggesting local recurrence and pelvic tumor implants (Fig. 1), the case was discussed with multidisciplinary team (MDT), and patient was proposed to CTX with future reevaluation for cytoreduction surgery with hyperthermic intraperitoneal chemotherapy (CS/HIPEC)
About half of the patients with CRC will have disease recurrence as peritoneal metastasis, and 10% of these will have isolated peritoneal disease.[2,3]. This case represents an example of metachronous peritoneal metastasis from primary rectal cancer and describes a multimodal and individual approach
Summary
Peritoneal carcinomatosis from colorectal cancer (CRC) represents a group of patients with metastatic disease associated with poor prognosis.In metastatic setting, chemotherapy (CTX) eventually with association of biologic agents is the standard of care, with improvement in progression-free survival and overall survival (OS). Peritoneal carcinomatosis from colorectal cancer (CRC) represents a group of patients with metastatic disease associated with poor prognosis.
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