Individualized body bioelectrical impedance parameters in newly diagnosed cancer children

Justa Carmen Columbié Regüeiferos,Taira Teresa Batista Luna,Tamara Rubio González,Soraida Candida Acosta Brooks,Luis Enrique Bergues Cabrales,Antonio Rafael Selva Castañeda,Victoriano Gustavo Sierra González,Maraelys Morales González,Manuel Verdecia Jarque

doi:10.1186/s41231-020-00062-1

Abstract

BackgroundThe bioelectric impedance analysis permits to estimate electrical parameters and body composition of subjects who are either apparently healthy or sick with different pathologies. The aim of this study is to individualize the analysis of body bioelectrical impedance parameters in newly diagnosed cancer children, by means of the bioelectrical impedance analysis for each age group, gender and cancer histological variety.MethodsThis retrospective cross-sectional study consisted of 43 pediatric patients with different histological varieties of cancer, ages from 2 to 17. The body electrical resistance and body capacitive electrical reactance were measured with the Bodystat 1500-MDD analyzer. From these two electrical parameters the body electrical impedance modulus and the body phase angle were calculated.ResultsThe results showed that 93.02% of cancer children were outside reference rectangles according to age groups and gender were showed. The values of body capacitive electrical reactance (72.5%) and body phase angle (90.70%) of these patients were below the lower limits of their respective rectangles. These findings were noticeable for patients who had solid tumors.ConclusionsThe BIA is feasible to individualize body bioelectrical parameters and body bioelectric state in newly diagnosed cancer children and how differ from those in apparently healthy subjects, for the same age group and gender. Additionally, the tumor electrical properties may have a noticeable role in changes of body bioelectric-physiological parameters of these newly diagnosed cancer children.

Highlights

The bioelectric impedance analysis permits to estimate electrical parameters and body composition of subjects who are either apparently healthy or sick with different pathologies
The aim of this study is to individualize the analysis of body bioelectrical impedance parameters in newly diagnosed cancer children, by means of the bioelectrical impedance analysis for each age group, gender and cancer histological variety
The unfilled triangle in the center of the Rr delimited with dashed line, named Rrd, symbolized the ordered pair ((R/H)r, (Xc/ H)r) for the female gender

Summary

Introduction

The bioelectric impedance analysis permits to estimate electrical parameters and body composition of subjects who are either apparently healthy or sick with different pathologies. In Cuba, cancer is the first cause of death for patients ages 5 to 15 and the second cause of death in children between 1 and 4 years old [2]. These statistics are similar to those reported in other countries [1]. Around 400 children are diagnosed each year in Cuba and 35 of them correspond approximately to Santiago de Cuba province. This number has increased to 60 in the last triennium [2]. Central nervous system tumors, lymphomas, bone tumors and renal tumors are the most common malignant neoplasms in pediatric patients (1–18 years old) [2,3,4]

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