Abstract
Cynomolgus monkeys, one of a number of primates phylogenetically close to humans, are commonly used in animal studies. The purpose of this study was to assess biological variations in hematological and serum biochemical parameters in cynomolgus monkeys. Summary statistics and reference intervals were calculated using data from 95 male and 95 female Chinese-bred cynomolgus monkeys aged 3 to 7 years showing no abnormalities during the breeding period. Within- and between-animal variations were estimated using a random-effect analysis of variance (ANOVA), then, a simple method that applies prior information was proposed to estimate individual reference intervals. Parameters including MCV, MCH, PT, ALP, total cholesterol, and creatinine appeared to show a large between-animal variation; thus, it is considered that individual reference intervals for these parameters would be relatively small in comparison with overall reference intervals.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
