Abstract

Abstract To study the transit times of individual red blood cells passing through cylindrical micropores and in order to evaluate sub-populations of cells with respect to their deformability, we have developed a new system, the Cell Transit Analyser (CTA). This computer assisted device provides the distribution of transit times τ for 5000 cells in about 1 minute. Experiments with red cells were designed to evaluate the flow behavior of both normal and abnormal cells. A statistical analysis of the results indicates a significant difference between control and rigid cells.

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