Abstract

In this paper we examine the consequences for models of radiation of allowing energy transfer events to diffuse before interacting with biological targets. In particular we describe a formulation of the theory of dual radiation action in which indirect action is explicitly included. The application of this formalism is illustrated by reanalyzing some of the data reported by Chapman et al. ( Radiat. Environ. Biophys. 1979, 16, 29) on the effects of the radioprotector dimethyl sulphoxide (DMSO) on mammalian cell survival.

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