Abstract
Introduction: Anthrax is a zoonotic infection that often becomes epidemic in endemic areas. It can be transmitted to humans through contact with infected animals. The most common manifestation is the appearance of eschar on the skin. Early detection as a screening for anthrax exposure can use serum anti PA Ig G antibody tests. This study aims to analyze the contact history and appearance of eschar on the skin against serum antibodies of people exposed to anthrax. Material and Methods: This analytical observational study used a cross-sectional design. It assessed the relationship of contact history and eschar to Ig G anti PA serum antibodies. To determine the significance of the association between the factors studied, an analysis using SPSS version 22.0 for windows was used, with a 95% confidence level. Result and Discussion: A total of 35 respondents who were exposed to anthrax in Gunungkidul District, Yogyakarta. Most of the respondents were women aged between 40 - 60 years and worked as farmers. It showed that Anti-PA Ig G antibodies are 40% positive, with 17% having a history of direct contact showing positive serology and 20% having eschar on skin with positive antibodies. It indicates a significant association between contact history and antibodies with p <0.05, but there is no significant difference in the appearance of eschar on the skin. Conclusion: There is a relationship between the results of serology with a history of contact with infected animals, so it’s very important information in efforts to prevent and screen anthrax in endemic areas.
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