Abstract
Indigenous Hepatitis E Virus Genotype 1 Infection, Uruguay
Highlights
To the Editor: Hepatitis E virus (HEV) is the only virus in the genus Hepevirus, which is the only member of the family Hepeviridae
For genotyping and phylogenetic analysis, a nested PCR was performed for the ORF1 RNA dependent RNA polymerase (RdRp) region [9]
Phylogenetic reconstruction of the ORF2–3 overlapping region showed that the HEV isolated in Uruguay clustered in genotype 1 with high bootstrap values (Figure, panel A)
Summary
To the Editor: Hepatitis E virus (HEV) is the only virus in the genus Hepevirus, which is the only member of the family Hepeviridae. HEV infection is of public health concern because it causes large epidemics and endemic waterborne outbreaks in Asia, Africa, and Latin America [2,3]. Genotype 1 was isolated in Asian and African countries and from Cuba and Venezuela in Latin America.
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