Indicators of antioxidant protection of the body of dairy cows depending on the phase of lactation and physiological state

Abstract

Relevance. Studies on the assessment of the pro- and antioxidant status of the body of productive animalsare relevant, since they are interconnected with health, the state of the immune and reproductive systems. There is a steadily growing body of information in the field of oxidative stress in animal husbandry and veterinary medicine, which indicates the general importance of antioxidant defense of the body with impaired health and productivity of ruminants. There is a growing need to translate this knowledge into practical proposals for livestock specialists and veterinarians.Methods. In order to study the indicators of antioxidant protection in the body of dairy cows depending on the month of lactation and the physiological state, the following groups of cows were formed in the conditions of the PZ Ladozhsky (Krasnodar district) in the winter period of 2021: dry; lactating: 1 month; 2 months; 3 months; 4 months; 5 months; 6–7 months. The following indicators were determined in the blood of the studied animals: the concentration of ceruloplasmin, products reacting with thiobarbituric acid, the total content of water-soluble antioxidants, the general antioxidant status, and the antioxidant activity of blood serum.Results. The results obtained indicate changes in the antioxidant status in the body of cows, depending on the physiological state and month of lactation. By 5–6 months of lactation in the blood of cows the maximum levels of accumulation of LPO products are observed and the level of ceruloplasmin decreases, and the maintenance of the overall antioxidant status is carried out at the expense of other water-soluble antioxidants. The most significant changes in the studied parameters are observed between dry and lactating cows. The results obtained will allow monitoring the health status of animals and will serve as the accumulation of a database for the development of reference values for indicators of the antioxidant status in the body of dairy cows, depending on the physiological state and phase of lactation.