Abstract

Aim: This study aimed to determine the indications and demographic profile of hepatic resection at Sher-I-Kashmir Institute of Medical Sciences (SKIMS), the performed types of hepatic resection, as well as assess the details of the operation and perioperative complications of hepatic resection.Methods: This is a prospective, retrospective observational study. The retrospective study period was from January 2005 to August 2015 and the prospective study period was from 2015 till 2017. Prospective patients were clinically evaluated by medical history and clinical examination and also underwent various investigations. The patients were scored on Child-Pugh and American Society of Anesthesiology (ASA) scores for risk stratification and prepared for surgery, which included segmentectomy to major liver resection. The retrospective data were obtained from the Medical Records Department (MRD). Statistical analysis was done on SPSS software 25.0 version (Armonk, NY: IBM Corp.).Results: This study included 122 patients with a male to female ratio of 1:1.59. The patients' age was between 1 and 73 years. The patients' most common complaint was right upper quadrant abdominal pain. The main established clinical diagnosis was oriental cholangiohepatitis (OCH) (36.9%) followed by carcinoma of gallbladder (CaGB) which accounted for 37 cases (30.4%). Liver metastases including solitary masses and multiple lesions were 10 cases (8.2%). Fifty-five patients underwent left lateral segmentectomy (45.1%) and mostly for OCH. Standard wedge resection was done in 30.7% of cases and for all cases of CaGB. The mean blood loss was 146.5 ml. A total of 37 patients had complications. Wound infection was the most common complication, occurring in 10 patients (8.2%).Conclusion: Patients with hepatobiliary pathology, necessitating liver resection are now routinely admitted to the Department of Surgical Gastroenterology in SKIMS, Srinagar. Patients are carefully evaluated and operated with a confirmed definitive diagnosis. The overall surgical outcome does not differ from India's best centers.

Highlights

  • Hepatic resection is the main cornerstone for primary and secondary liver tumors treatments showing compelling long-term oncological outcomes compared with other interventional or medical therapy in several hepatobiliary and oncological diseases [1,2,3,4]

  • Major hepatic resections are needed for both malignant conditions such as hepatocellular carcinoma (HCC), cholangiocarcinoma, and other rare types of malignant tumors, and benign primary liver tumors including giant hemangiomas and adenomas to achieve ideal therapeutic outcomes [9]

  • Standard wedge resection was done in 30.7% of cases and for all cases of carcinoma of gallbladder (CaGB)

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Summary

Introduction

Hepatic (liver) resection is the main cornerstone for primary and secondary liver tumors treatments showing compelling long-term oncological outcomes compared with other interventional or medical therapy in several hepatobiliary and oncological diseases [1,2,3,4]. Due to the improvements of the functional anatomy's knowledge, liver resections have evolved [8]. Major hepatic resections are needed for both malignant conditions such as hepatocellular carcinoma (HCC), cholangiocarcinoma, and other rare types of malignant tumors, and benign primary liver tumors including giant hemangiomas and adenomas to achieve ideal therapeutic outcomes [9]. Perioperative mortality after hepatic resection is 1-3% at high volume centers [10]

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