Index-Based Dietary Patterns and the Risk of Prostate Cancer among Iranian Men

Matin Ghanavati,Mehdi Movahed,Bahram Rashidkhani,Ehsan Hejazi,Afshin Rakhsha

doi:10.31557/apjcp.2019.20.5.1393

Abstract

Background and objective:The second most common cancer in men after lung cancer is prostate cancer (PC). Previous studies assessed the association between food items or food groups and the risk of PC, but diet quality indices are unique approaches to study any relations between diet and disease. Our objective was to investigate the effect of healthy eating index (HEI-2010) and Mediterranean-Style Dietary Pattern Score (MSDPS) on PC risk.Methods:In this case-control study, we recruited 97 patients with MS and 205 control subjects . Dietary intake was evaluted using a valid and reliable food frequency questionnaire. The HEI and MSDPS were calculated. Logistic regression was used to evaluate the relationship between HEI and MSDP scores and PC risk after adjusting the confounders.Results:In comparison to controls, cases had lower score on HEI (61 vs. 70.07; P< 0.001), and higher score on MSDP (26.20 vs. 24.49; P= 0.44). After comparing the highest and the lowest tertile of HEI, we observed a significant decreasing trend in the risk of PC (p for trend<0.001).Conclusion:Our findings suggested that a high quality diet, according to HEI, may decrease the risk of PC.

Highlights

Prostate cancer (PCa ) is the most diagnosed malignancy of men in Western countries (Grubb and Kibel, 2007)
Previous studies assessed the association between food items or food groups and the risk of prostate cancer (PC), but diet quality indices are unique approaches to study any relations between diet and disease
The associations between Mediterranean-Style Dietary Pattern Score (MSDPS) and Healthy Eating Index (HEI) 2010 and risk of PC were evaluated in this study

Summary

Introduction

Prostate cancer (PCa ) is the most diagnosed malignancy of men in Western countries (Grubb and Kibel, 2007). The incidence of PC in Asian countries, including Iran, is lower than that in Western populations (Hosseini et al, 2010). Our objective was to investigate the effect of healthy eating index (HEI-2010) and Mediterranean-Style Dietary Pattern Score (MSDPS) on PC risk. Logistic regression was used to evaluate the relationship between HEI and MSDP scores and PC risk after adjusting the confounders. Results: In comparison to controls, cases had lower score on HEI (61 vs 70.07; P< 0.001), and higher score on MSDP (26.20 vs 24.49; P= 0.44). Conclusion: Our findings suggested that a high quality diet, according to HEI, may decrease the risk of PC

Objectives

Methods

Results

Conclusion