Abstract

BackgroundThe objective of this study is to evaluate left atrial(LA) function and its prognostic value by two-dimensional speckle tracking echocardiography (STE) in patients with non-ST-segment-elevation acute myocardial infarction (NSTEAMI).MethodsGlobal longitudinal LA S/SR data obtained by 2D speckle imaging with automated software (Echo PAC, GE Medical).ResultsClinical variables and angiographic, echocardiographic, and STE parameters were studied in 65 patients with NSTEAMI (51 males and 14 females; mean age of 60.7 ± 9.8 years) who underwent elective PCI. The final study population consisted of 51 individuals (43 males and 8 females; mean age of 62.9 ± 11.1 years) and a 12 ± 3 months follow-up was performed. A total of 22 combined cardiovascular events(20 patients) occurred. With the use of Univariable Cox regression, all parameters were evaluated in the prediction of cardiac events, ischemic events, and/or cardiac death. According to ROC analysis, baseline mean global left atrial SRs (ROC area 0.82, p = 0.001) and baseline mean global left atrial SRe (ROC area 0.68, p = 0.036) were the only predictive variables.ConclusionsIn patients with NSTEAMI, we found that the novel global strain parameter of left atrial function is a valuable predictor of combined cardiovascular events over conventional echocardiography and may therefore be an important clinical tool for risk stratification in the acute phase of NSTEAMI.

Highlights

  • The objective of this study is to evaluate left atrial(LA) function and its prognostic value by twodimensional speckle tracking echocardiography (STE) in patients with non-ST-segment-elevation acute myocardial infarction (NSTEAMI)

  • Strain echocardiography had been validated as a prognostic indicator of cardiovascular diseases [6, 7].We hypothesized that patients with NSTEAMI have impaired function of LA as well as left ventricular (LV)

  • The aim of our study is to explore the utility of strain echocardiography in the assessment of LA function and prognostic value in patients with NSTEAMI undergoing elective percutaneous coronary intervention (PCI)

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Summary

Introduction

The objective of this study is to evaluate left atrial(LA) function and its prognostic value by twodimensional speckle tracking echocardiography (STE) in patients with non-ST-segment-elevation acute myocardial infarction (NSTEAMI). Coronary artery diseases (CAD) are the most common cardiac disease, which affect more than twenty million adults in China. Acute myocardial infarction (AMI), acting as a canonical component of CAD, contributes to approximately one million identified cardiac events every year. Strain echocardiography had been validated as a prognostic indicator of cardiovascular diseases [6, 7].We hypothesized that patients with NSTEAMI have impaired function of LA as well as left ventricular (LV).

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