Abstract

Introduction: Artemisinin (ART) is a novel antimalarial drug discovered in China that is quick and effective. The World Health Organization (WHO) has recommended ART-based combination therapies (ACT) as first-line drugs for the treatment of Plasmodium falciparum malaria in all malaria endemic countries. This has contributed to the recent significant decline in the global malaria burden. ART resistance was first detected along the Thai-Cambodian border and has been detected across mainland Southeast Asia. The continued spread of ART resistance will threaten malaria control programs.

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