Abstract

Accuracy of treatment planning systems may significantly influence the efficacy of brachytherapy. The purpose of this work is a detailed, varied and independent evaluation of an in‐house brachytherapy treatment planning software called STPS. Operational accuracy of STPS was investigated. Geometric tests were performed to validate entry and reconstruction of positional information from scanned orthogonal films. MCNP4C Monte Carlo code and TLDs were used for simulation and experimental measurement, respectively. STPS data were also compared with those from a commercial planning system (Nucletron PLATO). Discrepancy values between MCNP and STPS data and also those of PLATO and STPS at Manchester system dose prescription points (AL and AR) of tandem and ovoid configurations were 2.5%±0.5% and 5.4%±0.4%, respectively. Similar results were achieved for other investigated configurations. Observed discrepancies between MCNP and STPS at the dose prescription point and at 1 cm from the tip of the vaginal applicator were 4.5% and 25.6% respectively, while the discrepancy between the STPS and PLATO data at those points was 2.3%. The software showed submillimeter accuracy in its geometrical reconstructions. In terms of calculation accuracy, similar to PLATO, as attenuation of the sources and applicator body is not considered, dose was overestimated at the tip of the applicator, but based on the available criteria, dose accuracy at most points were acceptable. Our results confirm STPS's geometrical and operational reliability, and show that its dose computation accuracy is comparable to an established commercial TPS using the same algorithm.PACS number: 87.53.Jw

Highlights

  • The dose rate distributions around the above-mentioned applicators loaded with specific configurations of active and inactive pellets are usually calculated by treatment planning systems (TPSs), whereby each pellet is considered as a point source and the dose contributions from the active pellets are summed to determine the dose distribution around the applicator

  • Patients treated with a cylindrical applicator (C1, C2, and C3) The dose distribution around three different combinations of the spherical sources inside the cylindrical applicator used for treatment of patients was calculated by Monte Carlo (MC), Selectron treatment planning software (STPS), and PLATO calculations

  • DISCUSSION & CONCLUSIONS MC techniques have previously been used to study the dosimetry of gynechological brachytherapy

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Summary

Introduction

The Selectron treatment planning software (STPS) is an in-house TPS. It determines the dose distribution around different combinations of sources and spacers by assuming each active pellet as a point source. The Nucletron PLATO treatment planning system (Version UPS: 11.3) is a treatment planning system that uses the same dose calculation formalism.[8]. Such treatment planning systems, which are based on simple superposition, ignore the intersource attenuation and scattering of photons in the applicator. MC techniques have been widely used as a powerful tool for brachytherapy dosimetry to complement experimental measurements, for example, in characterization of the perturbing effects of applicators.[4,5,9,10,11,12]

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