Abstract
Ancestry Informative Markers InDels (AIM-InDels) show high allele frequency variation between ancestral populations and are useful to estimate individual and population ancestry. Our goal was to characterize the frequencies of 46 AIM-InDels in a population sample of 50 individuals from Barranquilla city, Atlantic Department in Colombia. The ancestral components were calculated according to the methodology described in [1]; using STRUCTURE v2.3.3 with a burnin length of 100,000 followed by 100,000 MCMC, with a K=3, considering the “Admixture Model” and correlated allele frequencies. As parental populations, the genetic profiles of 322 individuals (Africans: 105 Europeans: 158, Native Americans: 59) [1] and 42 Native American individuals [8] were used. The contribution of each founder population was estimated in: 24.7% of African, 27.6% of Native American and 47.7% of European. These findings reveal different admixture histories of the studied population, and generate reliable ancestry estimates useful to investigate association between ancestry and genetic complex disorders.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Forensic Science International: Genetics Supplement Series
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
