Abstract
Background A multiple-test strategy in often needed in the evaluation of patients (pts) with suspected coronary artery disease (CAD). Cardiac magnetic resonance (CMR) has potential advantages in this context allowing simultaneous evaluation of ventricular function, myocardial perfusion and scar detection with high spatial resolution and no ionizing radiation exposure. We aimed to compare the diagnostic accuracy of adenosine stress CMR myocardial perfusion imaging (CMR-MPI) with exercise treadmill test (ETT) for detection of CAD using invasive fractional flow reserve (FFR) as the reference standard, and to assess the best performing diagnostic algorithm using these tests in patients with suspected CAD.
Highlights
A multiple-test strategy in often needed in the evaluation of patients with suspected coronary artery disease (CAD)
We aimed to compare the diagnostic accuracy of adenosine stress Cardiac magnetic resonance (CMR) myocardial perfusion imaging (CMR-MPI) with exercise treadmill test (ETT) for detection of CAD using invasive fractional flow reserve (FFR) as the reference standard, and to assess the best performing diagnostic algorithm using these tests in patients with suspected CAD
CMR-MPI exams were evaluated by two independent cardiologists blinded to the results of ETT
Summary
A multiple-test strategy in often needed in the evaluation of patients (pts) with suspected coronary artery disease (CAD). Cardiac magnetic resonance (CMR) has potential advantages in this context allowing simultaneous evaluation of ventricular function, myocardial perfusion and scar detection with high spatial resolution and no ionizing radiation exposure. We aimed to compare the diagnostic accuracy of adenosine stress CMR myocardial perfusion imaging (CMR-MPI) with exercise treadmill test (ETT) for detection of CAD using invasive fractional flow reserve (FFR) as the reference standard, and to assess the best performing diagnostic algorithm using these tests in patients with suspected CAD
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