Increasing prevalence of type 2 diabetes mellitus and impact of ethnicity in north Sudan

Abstract

BackgroundDiabetes mellitus constitutes a global health threat, with increasing burden of disease in low and middle-income countries witnessing ongoing epidemiological transition including Sudan. AimsTo study the prevalence of type 2 diabetes mellitus (T2DM) and prediabetes and determine the relationship to gender, age, waist circumference, body mass index, residence and ethnicity among the adult population in north Sudan. MethodsA cross-sectional, population-based study in Northern State and River Nile State using random multi-stage cluster sampling targeting 5376 participants from 14 localities divided into 60 urban and 40 rural clusters. In each cluster, 60 households were studied. Blood glucose level and anthropometric measurements were recorded and a questionnaire containing demographic data was obtained from each participant. ResultsThe prevalence of T2DM among participants was 18.7% and prediabetes was 12.9%. Among people living with T2DM, 694(71.0%) were known cases of T2DM, whereas 284(29.0%) were newly diagnosed cases. The significant associated risk factors for T2DM included urban residence (AOR 1.23, 95%CI 1.09–1.41), age above 60 years (AOR 4.77, 95%CI 4.04–5.63), obese BMI (AOR 1.26, 95%CI 1.03–1.55) and central obesity (AOR 1.39, 95%CI 1.14–1.68). Compared to indigenous population, individuals of Egyptian descents (AOR 1.28, 95%CI 1.04–1.57) and mixed origin (AOR 1.24, 95%CI 1.04–1.48) had increased risk of T2DM. ConclusionThe prevalence of T2DM and prediabetes in north Sudan have increased significantly since 1996 with variations between ethnicities which showed to be an independent risk factor for T2DM. Health authorities are recommended to set plans to meet the health needs of these communities.