Abstract

PurposeIncreasing influenza vaccination coverage in healthcare workers is a challenge. Especially during the ongoing COVID-19 pandemic, high vaccination coverage should be attained. This review analyzed strategies to increase influenza vaccination coverage in healthcare workers.MethodsA literature search using PubMed was conducted and 32 publications on influenza vaccination campaigns for healthcare workers were reviewed for key interventions and resulting vaccination coverage.ResultsAmong key interventions analyzed, mandatory vaccination policies or multifaceted campaigns including a vaccinate-or-wear-a-mask policy as well as mandatory declination reached vaccination coverage in healthcare workers of over 90%. Although campaigns solely based on education and promotion or on-site-vaccination did not regularly exceed an absolute vaccination coverage of 40%, a substantial relative increase in vaccination coverage was reached by implementation of these strategies.ConclusionMandatory vaccination policies are effective measures to achieve high overall vaccination coverage. In clinics where policies are infeasible, multifaceted campaigns comprising on-site vaccination, vaccination stands and educational and promotional campaigns as well as incentives should be implemented. Lessons learned from influenza campaigns could be implemented in future SARS-CoV-2 vaccination campaigns.

Highlights

  • The analysis shows that vaccination campaigns are generally based on multifaceted vaccination strategies

  • Vaccination strategies are implemented on different levels of initial vaccination rate

  • Most of the published vaccination strategies resulted in an increase in vaccination rates independent of the initial vaccination rate

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Summary

Introduction

Influenza is a highly contagious disease, causing 4.0–8.8 respiratory deaths per 100 000 individuals annually worldwide [1]. Vaccination is the most effective form of influenza prevention. The World Health Organization (WHO) recommends annual influenza vaccination for these vulnerable populations as well as healthcare workers (HCW) [2]. HCW may transmit influenza to vulnerable patients, thereby compromising patient safety [3]. Despite this recommendation, vaccination rates among HCW are low ranging from 15.6 to 63.2% (median 30.2%) in Europe [4]. Other than allergies against vaccine compounds, there are no medical contraindications for influenza vaccination. If allergy to egg protein is known, a cell- or recombinant-based vaccine can be used [5].

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