Increasing Incidence ofClostridium difficile-associated Disease, Singapore

Poh Lian Lim,Brenda Ang,Frederico Dimatatac,Li Min Ling,Tamuno Alfred,Timothy M.S Barkham

doi:10.3201/eid1409.070043

Abstract

Increasing Incidence of<i>Clostridium difficile</i>-associated Disease, Singapore

Highlights

We examined the incidence of C. difficile among hospitalized patients in Singapore from 2001 through 2006 and conducted a case–control study to evaluate risk factors for testing positive for C. difficile toxin (CDT) in our population
We calculated Clostridium difficile–associated disease (CDAD) incidence using the number of patients testing positive for CDT per 10,000 patient days from 2001 through 2006
We examined antimicrobial drug use within 30 days of admission and within 30 days of CDT testing

Summary

Introduction

5. Fawley WN, Freeman J, Smith C, Harmanus C, van den Berg RJ, Kuijper EJ, et al Use of highly discriminatory fingerprinting to analyze clusters of Clostridium difficile infection cases due to epidemic ribotype 027 strains. 6. Long S, Fenelon L, Fitzgerald S, Nolan N, Burns K, Hannan M, et al First isolation and report of clusters of Clostridium difficile PCR 027 cases in Ireland. 8. Goorhuis A, Van der Kooi T, Vaessen N, Dekker FW, Van den Berg R, Harmanus C, et al Spread and epidemiology of Clostridium difficile polymerase chain reaction ribotype 027/toxinotype III in The Netherlands.

Results

Conclusion