Abstract
Background: Era of contraception, abortions, [20th, 21st centuries] implemented as family welfare schemes, witnessed increased global incidence of Type 2 diabetes mellitus, systemic hypertension. Objectives: Altruistic association of contraception [if any], with increasing diabetes mellitus, systemic hypertension, was sought after. Methods: In 2012, retrospective analysis of, prevalence of diabetes mellitus, systemic hypertension, in 350 patients of 20 - 35 years, 35 - 50 years, >50 years, age groups, data collected by convenient, stratified random sampling, from different geographical locations, between 2003-2012 and its association with presence, absence of contraception, abortion was undertaken; simultaneously, serum estrogen levels obtained from 105 patients, were also analysed. Results: 10 - 45 fold increase in Type 2 diabetes mellitus was seen in contraceptive users of >20 years to >50 years; 15 - 50 fold increase in incidence of systemic hypertension was seen in contraceptive users of >20 years to >50 years. Endogenous estrogen was reduced below normal in 75% of contraceptive users, and 25% of contraceptive users had low normal serum estrogen. Cholesterol deprived diet, due to decreased synthesis of endogenous estrogen, androgen also was associated with 50% increase in diabetes mellitus, systemic hypertension. Conclusion: Concept is acquired contraception, abortion status, with smashed fragmentation of germ cells, reduced endogenous estrogen, androgen, results in defaulted genomic repertoire, deranged cell metabolism, increased incidence of diabetes mellitus, systemic hypertension as part of metabolic syndrome. Contraception reversal declined the diseases as a cause and effective phenomenon.
Highlights
People in about 1989 complained of weight gain, low back aches, were detected to have diseases, including diabetes mellitus, systemic hypertension, and were attributing to aftermath of tubectomy-puerperal permanent sterilisation, though it was ignored by medical personnel, since contraception was presumed to be without side effects, [permitted by Life Sciences, without evidence base or studies prior to or after implementation of family welfare schemes, implemented without therapeutic indication], and the contraceptive procedures as such were uneventful
Cholesterol deprived diet―oil without fatty acids, sunflower refined, bleached oil consumption showed a 50% increase of osteoporosis, 5 fold increase in diabetes mellitus in young adults before marriage [i.e. in our country premarital sex is prohibited, considered as adultery, but contraception is practised in life partners, ~98% as part of family welfare schemes, to reduce population, human race, without evidence base for safety or therapeutic indication]
Endogenous estrogen was grossly reduced to ~5 - 8 pgm in 75% of people using contraception: Figure 3, in 20 to
Summary
People in about 1989 complained of weight gain, low back aches, were detected to have diseases, including diabetes mellitus, systemic hypertension, and were attributing to aftermath of tubectomy-puerperal permanent sterilisation, though it was ignored by medical personnel, since contraception was presumed to be without side effects, [permitted by Life Sciences, without evidence base or studies prior to or after implementation of family welfare schemes, implemented without therapeutic indication], and the contraceptive procedures as such were uneventful. Abortions, [20th, 21st centuries] implemented as family welfare schemes, witnessed increased global incidence of Type 2 diabetes mellitus, systemic hypertension. Objectives: Altruistic association of contraception [if any], with increasing diabetes mellitus, systemic hypertension, was sought after. Methods: In 2012, retrospective analysis of, prevalence of diabetes mellitus, systemic hypertension, in 350 patients of 20 - 35 years, 35 - 50 years, >50 years, age groups, data collected by convenient, stratified random sampling, from different geographical locations, between 2003-2012 and its association with presence, absence of contraception, abortion was undertaken; simultaneously, serum estrogen levels obtained from 105 patients, were analysed. Cholesterol deprived diet, due to decreased synthesis of endogenous estrogen, androgen was associated with 50% increase in diabetes mellitus, systemic hypertension. Conclusion: Concept is acquired contraception, abortion status, with smashed fragmentation of germ cells, reduced endogenous estrogen, androgen, results in defaulted genomic repertoire, deranged cell metabolism, increased incidence of diabetes mellitus, systemic hypertension as part of metabolic syndrome. Contraception reversal declined the diseases as a cause and effective phenomenon
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