Abstract
Extracted from text ... VOLUME 3 NUMBER 3 ? AUGUST/SEPTEMBER 2006 111 SA JOURNAL OF DIABETES & VASCULAR DISEASE EDITORIAL Introduction Obesity, especially intra-abdominal adiposity, drives the premature onset and progression of type 2 diabetes and accentuates cardiovascular risk.1 The act of losing weight by diet and exercise substantially benefits glycaemic control and improves insulin sensitivity, while protracted weight loss reduces cardiovascular risk markers in obese type 2 diabetic patients.2 Non-pharmacological approaches to weight control are fraught with low efficacy and poor compliance. Why then is the role of antiobesity agents such a controversial issue in the management of the overweight type 2 ..
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