Increased weight gain and sucrose intake during extinction of nicotine self-administration in adult male rats

Abstract

level. The purpose of this studywas to test the hypothesis thatmarijuana and alcohol use would increase the odds of girls engaging in sexual intercourse on the same day. Methods: The sample consisted of 30 truant girls between the ages of 13-18 years. A Timeline Follow-Back calendar assessment was used to collect data on marijuana use, alcohol use, and sexual intercourse over a 90-day period. Results: Results from a series of General Estimating Equation models analyzing 2700 days demonstrated that usingmarijuana on a given day increased the odds of engaging in sexual intercourse, OR=2.89, 95% CI [1.95, 4.28], p< .001. Alcohol use did not change the odds of engaging in sexual intercourse on the same day; however, frequency of alcohol use did increase the odds of engaging in sexual intercourse, OR=1.12, 95% CI [1.02, 1.07], p=0.001. When all problem behaviors were included in the same model, frequent marijuana users were less likely to engage in sexual intercourse than infrequent users, OR=0.99, 95% CI [0.98, 0.9995], p=0.04. Conclusions: This study found an important distinction between infrequent and frequent alcohol and marijuana users and their engagement in sexual intercourse. Consistent with previous findings, frequent alcohol use was related to increased rates of sexual intercourse and should be a focus of early intervention. Further, frequent female marijuana users may have less interest in engaging in sexual intercourse or have some common factor which reduces their frequencyof engaging in sexual intercourse. Intervention/prevention programs should address the differential effects of frequency of marijuana and alcohol use on the odds of engaging in sexual intercourse among girls. Financial support: This study was supported by National Institute on Drug Abuse grant number R34DA029871.