Abstract
Factor XI deficiency is an autosomal recessive (AR) bleeding disorder frequently seen in the Ashkenazi Jewish population but less common among other ethnicities. Although carriers of AR disorders are typically asymptomatic, Factor XI deficiency carriers can have reduced factor XI levels and experience increased bleeding. Any deficiency in factor XI may lead to propensity to bleed; however, the bleeding risk is unpredictable as there is poor correlation with factor XI level. As ECS becomes more commonplace in the IVF clinic and many ECS panels include the F11 gene, an increasing number of patients are being identified to carry or be affected with factor XI deficiency.
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