Abstract
We have investigated the effect of malaria infection on the urine biochemistry and the renal and hepatic levels of total antioxidant capacity (TAC) in female BWF1 lupus mice. A total of 30 female BWF1 lupus mice were divided into three groups as follows: group (I) control group; group (II) lupus mice infected with live Plasmodium. chabaudi; group (III) lupus mice infected with irradiated P. chabaudi. Mice were killed at day 14 post-infection and plasma samples were collected. live P. chabaudi infection was associated with decreased level of glucose in urine (glucosuria), increased urinary level of both ketones (ketonuria) and blood (hematuria). Additionally, live P. chabaudi infection was associated with increased level of TAC in the renal tissue with decreased level of TAC in the hepatic tissue of infected mice. In conclusion, P. chabaudi infection has a direct effect on the urine biochemistry and the renal and hepatic levels of TAC in BWF1 mice.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
