Increased Risk of Subsequent Skin Melanoma in Patients with Retinoblastoma: SEER-Based Results

Abstract

In their article entitled “Increased risk of skin cancer in 1,851 long-term retinoblastoma survivors,” Kleinerman et al. (2021) reported on the risk of skin cancer among long-term retinoblastoma (RB) survivors from 1914 to 2006. By calculating standardized incidence ratios (SIRs), the authors reported the risk of invasive melanoma in patients with hereditary RB to have stood at 13.9 compared with that in the general population. For patients with nonhereditary RB, the SIR stood at 1.4.