Abstract
Male reproductive health is a marker of individual somatic health and more recently has been associated with familial health. Familial studies offer a unique opportunity to quantity the effect of genetic and shared environmental exposures on male subfertility and birth outcomes. We have previously shown an increased risk of death from congenital malformations (CM) in relatives of men with lower semen parameters. We examine the association between markers of poor semen quality in men presenting for infertility workup and any CM in their relatives, within the Utah Population Database (UPDB).
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