Abstract
Duodenal adenomas are common in familial adenomatous polyposis (FAP). It is, however, not known whether patients with duodenal adenomas without FAP should undergo routine colonoscopy for detection of colorectal neoplasia. The aim of this study was to evaluate the correlation between the incidence of sporadic duodenal adenomas and colorectal neoplasias. Patients with sporadic duodenal adenomas and without FAP were retrospectively evaluated for the existence of colorectal neoplasia. Each patient was compared with three randomly selected age and sex-matched controls. Sporadic duodenal adenomas were diagnosed by endoscopy in 51 patients, of whom 48 underwent additional colonoscopy. The mean age of the 48 analysed patients was 66 (40-83) years (women:men=23 : 25). Colorectal neoplasia was significantly more common among patients with duodenal adenomas (75% vs. 27.7%; P<0.05; odds ratio=7.80 [95% confidence interval 3.48-17.72]). In this case control study, the prevalence of colorectal adenomas in patients with sporadic duodenal adenomas without FAP was significantly increased compared with the average population. Therefore, patients with duodenal adenomas should be screened for the occurrence of colorectal adenomas.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: European Journal of Gastroenterology & Hepatology
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
