Increased MR Signal Intensity in the Pronator Quadratus Muscle: Does It Always Indicate Anterior Interosseous Neuropathy?

Abstract

The objective of this study was to assess the prevalence of increased signal intensity in the pronator quadratus in the general patient population. Using region-of-interest measurements, we measured the signal intensity of the pronator quadratus and of an adjacent flexor muscle. In addition, we performed independent subjective assessments of the pronator quadratus. Increased signal intensity in the pronator quadratus is a frequent normal finding of unclear etiology and is not related to disease. Familiarity with this normal phenomenon is important to avoid overdiagnosis of denervation due to anterior interosseous nerve entrapment.