Abstract
Ebola virus RNA can reside for months or years in semen of survivors of Ebola virus disease and is probably associated with increased risk for cryptic sexual transmission of the virus. A modified protocol resulted in increased detection of Ebola virus RNA in semen and improved disease surveillance.
Highlights
Ebola virus RNA can reside for months or years in semen of survivors of Ebola virus disease and is probably associated with increased risk for cryptic sexual transmission of the virus
During 2013–2016, Ebola virus (EBOV; family Filoviridae, genus Ebolavirus, species Zaire ebolavirus) caused an unprecedented outbreak of Ebola virus disease (EVD) that began in Guinea and subsequently affected Liberia, Sierra Leone, and, to a much lesser degree, several other countries in West Africa
The large number of EVD survivors enabled detailed studies, such as the Partnership for Research on Ebola Virus (PREVAIL) III study [3], which aimed at characterizing potential EVD sequelae and EBOV persistence in a cohort of 1,144 EVD survivors in Liberia over the course of 5 years
Summary
Ebola virus RNA can reside for months or years in semen of survivors of Ebola virus disease and is probably associated with increased risk for cryptic sexual transmission of the virus. Author affiliations: National Institutes of Health, Frederick, Maryland, USA Dighero-Kemp, J.H. Kuhn, L.E. Hensley); National Public Health Institute of Liberia, Monrovia, Liberia
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