Increased Intracranial Pressure Following Treatment of Cystic Fibrosis

Abstract

Elevated intracranial pressure in children with cystic fibrosis has been previously attributed to vitamin A deficiency,1,2 which is a well recognized cause of increased intracranial pressure.3 Although there are several reports of suture diastasis after improvement of poor nutritional status,4-6 only one similar patient with a bulging fontanel following treatment of cystic fibrosis could be found in the literature.7 We have recently encountered two patients who developed bulging anterior fontanels soon after beginning treatment for cystic fibrosis. Both patients remained asymptomatic. A lumbar puncture demonstrated elevated intracranial pressure in one patient. CASE REPORTS Case 1 A 4½-month-old white male infant was admitted for evaluation of poor weight gain, vomiting, and intermittent diarrhea.